药品详情：
【阿米替林amitriptyline 简述】
本品为临床常用的TCA,其抗抑郁作用与丙米嗪极为相似，与后者相比，本品对5-HT再摄取的抑制作用强于对NA再摄取的抑制;其镇静作用与抗胆碱作用也较明显。
【阿米替林amitriptyline 适应症】
①用于治疗各型抑郁症或抑郁状态。对内因性抑郁症和更年期抑郁症疗效较好，对反应性抑郁症及神经官能症的抑郁状态亦有效。对兼有焦虑和抑郁症状的患者，疗效优于丙米嗉。与电休克联合使用于重症抑郁症,可减少电休克次数。
②用于缓解慢性疼痛。
③亦用于治疗小儿遗尿症、儿童多动症。
【阿米替林amitriptyline 规格】
本品为片剂，每片含有效成份2mg/4mg等多种规格。
【阿米替林amitriptyline 服用方法】
由于剂型及规格不同，用法用量请仔细阅读药品说明书或遵医嘱。
【阿米替林amitriptyline 注意事项】
严重肝肾功能不全、支气管哮喘者慎用。
【阿米替林amitriptyline 不良反应】
常见有口干、嗜睡、便秘、视力模糊、排尿困难、心悸。偶见心律失常、眩晕、运动失调、癫痫样发作、体位性低血压、肝损伤及迟发性运动障碍。有报道偶有加重糖尿病症状。
Elavil(amitriptline)
Neuropathic pain is pain caused by damage or disease affecting the somatosensory nervous system.[1] Neuropathic pain may be associated with abnormal sensations called dysesthesia or pain from normally non-painful stimuli (allodynia). It may have continuous and/or episodic (paroxysmal) components. The latter resemble stabbings or electric shocks. Common qualities include burning or coldness, "pins and needles" sensations, numbness and itching.
Up to 7%-8% of the European population is affected, and in 5% of persons it may be severe.[2][3] Neuropathic pain may result from disorders of the peripheral nervous system or the central nervous system (brain and spinal cord). Thus, neuropathic pain may be divided into peripheral neuropathic pain, central neuropathic pain, or mixed (peripheral and central) neuropathic pain.
Adverse effects
The predominant adverse effects are CNS depression and cardiovascular effects—which are mild and well tolerated, but psychoactive side effects limit their use.[26]
注：药品如有新包装,以新包装为准。以上资讯来源于网络或由高等医药院校的学生志愿者翻译（如有错漏，请帮忙指正）,仅供医护人员内部讨论,不作任何用药依据,具体用药指引,请咨询主治医师。
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