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布斯帕BusPIRone

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布斯帕BusPIRone
药品名称:布斯帕BusPIRone
药品别名:盐酸布斯帕、布司必隆、布斯哌隆、丁螺环酮、Buspar
英 文 名:BusPIRone
药品价格:$ 美国市场售价 33.35 美元
研发公司:
适 用 症:适用于泛发性焦虑症的治疗,对各种身心症状有良好的疗效
型号规格:5mg/10mg/15mg/30mg多种型号,每瓶100片装
药品详情:

【布斯帕BusPIRone 简述】
 
    布斯帕BusPIRone别名盐酸布斯帕、布司必隆、布斯哌隆、丁螺环酮、Buspar,是一类神经系统抗焦虑药物。

布斯帕BusPIRone_香港济民药业

布斯帕BusPIRone_香港济民药业

布斯帕BusPIRone_香港济民药业


 
 
【布斯帕BusPIRone 适应症】
 
    布斯帕BusPIRone适用于泛发性焦虑症的治疗,对各种身心症状有良好的疗效。 
 
【布斯帕BusPIRone 规格】
 
    本品为片剂,分为5mg/10mg/15mg/30mg多种型号,每瓶100片装;    
 
【布斯帕BusPIRone 服用方法】
 
1.开始时每次5mg,每天2~3次,以后根据病情和耐受情况调整用量,每隔2~3天加5mg,可增至每天20~30mg,至达到预期的疗效。每天最高口服剂量不超过60mg。
 
2.老人使用本药应从小剂量开始,一般不超过15mg/天。 
 
【布斯帕BusPIRone 注意事项】
 
1.老年人应减量。
 
2.应监测患者焦虑的减轻程度。
 
3.服药期间禁止饮酒。
 
4.用药期间不宜驾驶车辆和操作机械。
 
5.布斯帕显效时间2周左右。
 
6.布斯帕不宜与中枢抑制药、降压药、抗凝药、避孕药及单胺氧化化酶抑制药(MAOI)合用。
 
【布斯帕BusPIRone 不良反应】
 
1.常见的不良反应有头晕、头痛、恶心、不安、烦躁。
 
2.少见的不良反应有视物不清、注意力涣散、萎靡、口干、肌肉痛、肌肉痉挛、抽动、肌强直、耳鸣、激动、失眠、神经过敏、腹泻、胃部不适、梦魇、多梦、疲乏无力。
 
3.罕见的不良反应有胸痛、精神错乱、抑郁、心动过速、肌无力、肌肉麻木、手足无力。

Bispar(BusPIRone)

 
Buspirone, sold under the brand name Buspar among others, is a medication primarily used to treat anxiety disorders particularly general anxiety disorder.[9][10] Benefits are support for short term use.[11] It is not useful for psychosis.[9] It is taken by mouth.[9] It may take up to four weeks for an effect.[10]
 
Common side effects include nausea, headaches, dizziness, and trouble concentrating.[9][11]Serious side effects may include hallucinations, serotonin syndrome, and seizures.[11] Use in pregnancy appears to be safe but has not been well studied, while use during breastfeedingis not recommended.[12][11] How it works is not clear but it is unrelated to benzodiazepines.[9]
Buspirone was first made in 1968 and approved for medical use in the United States in 1986.[9][10] It is avaliable as a generic medication.[11] A month supply in the United Kingdom costs the NHS about 10 £ as of 2019.[11] In the United States the wholesale cost of this amount is about 2.65 USD.[13] In 2016 it was the 90th most prescribed medication in the United States with more than 8 million prescriptions.[14]
 
 
Medical uses
Anxiety
Buspirone is used for the short-treatment of anxiety disorders or symptoms of anxiety.[15][16][17][18][19] It is generally less preferred than selective serotonin reuptake inhibitors (SSRIs).[10]
Buspirone has no immediate anxiolytic effects, and hence has a delayed onset of action; its full clinical effectiveness may require 2 to 4 weeks to manifest.[20] The drug has been shown to be similarly effective in the treatment of GAD to benzodiazepines including diazepam, alprazolam, lorazepam, and clorazepate.[4] Buspirone is not known to be effective in the treatment of other anxiety disorders besides GAD,[21] although there is some limited evidence that it may be useful in the treatment of social phobia as an adjunct to selective serotonin reuptake inhibitors (SSRIs).[4][22]
Sexual dysfunction
There is some evidence that buspirone on its own may be useful in the treatment of hypoactive sexual desire disorder (HSDD) in women.[23]
Miscellaneous
Buspirone is not effective as a treatment for benzodiazepine withdrawal, barbiturate withdrawal, or alcohol withdrawal/delirium tremens.[24]
 
Contraindications
 
Buspirone has these contraindications:[25][26]
 
§  Hypersensitivity to buspirone
 
§  Metabolic acidosis, as in diabetes
 
§  Should not be used with MAO inhibitors
 
§  Severely compromised liver and/or kidney function
 
Overdose
 
Buspirone appears to be relatively benign in cases of single-drug overdose, although no definitive data on this subject appear to be available.[27] In one clinical trial, buspirone was administered to healthy male volunteers at a dosage of 375 mg/day, and produced side effects including nausea, vomiting, dizziness, drowsiness, miosis, and gastric distress.[15][16][18] In early clinical trials, buspirone was given at dosages even as high as 2,400 mg/day, with akathisia, tremor, and muscle rigidity observed.[28] Deliberate overdoses with 250 mg and up to 300 mg buspirone have resulted in drowsiness in about 50% of individuals.[28] One death has been reported in association with 450 mg buspirone together with alprazolam, diltiazem, alcohol, cocaine.[28]
 
 




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