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Novatech无菌滑石粉颗粒(STERITALC)

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Novatech无菌滑石粉颗粒(STERITALC)
药品名称:Novatech无菌滑石粉颗粒(STERITALC)
药品别名:STERITALC
英 文 名:Novatech
药品价格:$ 请咨询微信客服
研发公司:
适 用 症:用于滑石汾胸膜固定术
型号规格:本品有多种规格。
药品详情:

Novatech无菌滑石粉颗粒(STERITALC) 简述】
 
    无菌滑石粉颗粒STERITALC是在法国开采、经过专门处理、用于医疗用途的滑石粉颗粒(主要用于滑石粉胸膜固定术)。颗粒不可溶,并会导致永久胸膜固定。与四环素类药物相比,滑石粉更有效,痛楚更少。

Novatech无菌滑石粉颗粒(STERITALC)_香港济民药业
 
【Novatech无菌滑石粉颗粒(STERITALC) 适应症】
 
    本品主要用于滑石汾胸膜固定术。
 
    1、慢性胸膜炎,主要是恶性胸膜炎;
 
    2、自发性气胸;
 
    3、胸膜固定术适用的其他情况。
 
【Novatech无菌滑石粉颗粒(STERITALC) 规格】
 
    本品含有多种规格,详见下表:
Novatech无菌滑石粉颗粒(STERITALC)_香港济民药业
 
【Novatech无菌滑石粉颗粒(STERITALC) 使用方法】
 
    根据医生的指示、诊断的结果、病人的年龄和健康状态进行服用。
 
    用于胸腔积液的服用剂量范围为3至6克,用于自发性气胸的剂量一般不超过2克,如果积液蓄积胸膜腔,应先排干积液,再使用滑石颗粒。
 
【Novatech无菌滑石粉颗粒(STERITALC) 注意事项】
 
    本品是不可溶解的,并导致永久胸膜固定术。本品不含石棉和胶乳。
 
    本品在使用前必须经无菌处理,粒度测量经过完美处理和控制,从而将在胸膜壁层间扩散的风险降至最低。
 
【Novatech无菌滑石粉颗粒(STERITALC) 不良反应】
 
    本品的副作用类似于四环素类药物(cyclines),可通过使用1%的利多卡因直接施用在胸膜或通过浆液使用,以减低任何使用时引起的疼痛。


STERITALC® consists of talcum which is mined in France and is specifically processed for medical use (talcum pleurodesis).

STERITALC® is suited for all indications of pleurodesis. It is non-soluble and induces permanent pleurodesis. Compared with tetracyclines, talcum is more effective and less painful.

As a rule, for malignant indications 3 to 5 g are used, for treatment of spontaneous pneumothorax 2 g are sufficient in most cases.

A critical side effect of talcum pleurodesis can be ARDS (Acute Respiratory Distress Syndrome). A possible cause of ARDS may be the systemic dissemination of talcum. In some cases, after application in the pleural cavity, talcum was found in other organs (kidneys, spleen, liver), too. The literature assumes that there is a relation between the talcum particle size and the systemic dissemination of talcum: smaller talcum particles appear to disseminate more than larger ones1). The clinical picture also shows the effect of different particle sizes: talcum with a mean particle size below 15 µm induced stronger systemic and pulmonary inflammation reactions than talcum with a mean particle size of 25 µm.

STERITALC®, produced by Novatech, is specifically calibrated to a mean particle size of 25 µm in order to avoid systemic dissemination. Animal3) and clinical studies2) show the lesser systemic dissemination.

A multi-center study showed that STERITALC® with its calibrated particle size can be safely used for pleurodesis of malignant pleural effusions. None of more than 550 patients developed ARDS4). The authors recommend to use no other talcum.

Another cause of ARDS may be a sepsis due to unsterile talcum, or talcum containing endotoxines5). This, too, can be excluded when STERITALC® is used, because STERITALC® is free of endotoxines and comes sterile.





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